The use of natural products in skincare and cosmetics has been on the rise in recent years, as consumers seek more eco-friendly and non-toxic alternatives to traditional synthetic ingredients. A new study has shown promising results for the use of sweet cherry (Prunus avium L.) fruit extract in skincare products, highlighting its potential to improve epidermis function without causing cytotoxicity or irritation.
Natural products have long played a crucial role in traditional and modern medicine, with many current drugs derived from natural sources. Besides medicine and therapeutics, natural products are widely used in various industries, including nutrition, skincare products, and nanotechnology.
The study aimed to evaluate the effects of sweet cherry fruit extract from the Greek native cultivar ‘Vasiliadi’ on human 2D and 3D in vitro skin models. Researchers focused on 2D culture of primary normal human epidermal keratinocytes (NHEK) treated with the sweet cherry fruit extract. The first step was to determine the potential cytotoxicity of the fruit extract by measuring intracellular ATP levels. Researchers also assessed the potential skin irritability of the extract using a 3D skin model.
To better understand the bioactivity of the sweet cherry fruit extract, the study employed qPCR to examine the expression of various genes involved in skin functions. The experiments demonstrated that the sweet cherry fruit extract is non-toxic in 2D keratinocyte culture and non-irritant in the 3D skin model. Additionally, the results revealed that the extract influences essential pathways for optimal epidermis function, such as cell proliferation, immune response, and inflammatory response.
These findings suggest that sweet cherry fruit extract possesses significant activity in epidermis function without any potential for cytotoxicity or skin irritability. This makes it a promising active ingredient for skincare products, particularly for those seeking natural alternatives to synthetic components.
The use of natural ingredients in skincare has numerous potential benefits, including reducing the risk of allergic reactions, avoiding potentially harmful chemicals, and aligning with consumers’ growing focus on environmental sustainability. The promising results of this study on sweet cherry fruit extract could pave the way for its incorporation into a wide range of skincare products, such as moisturizers, cleansers, and serums.
Furthermore, the study’s findings may also have broader implications for the skincare industry as a whole. As more research is conducted on natural ingredients and their effects on skin health, companies may increasingly turn to these natural alternatives to synthetic ingredients, both for their potential benefits and to meet consumer demand for eco-friendly, non-toxic products.
However, it is essential to recognize that this study represents just one piece of the puzzle. Further research is needed to better understand the full range of potential benefits and applications of sweet cherry fruit extract in skincare products. For example, future studies may explore the extract’s potential effects on specific skin concerns, such as acne or eczema, or its potential to enhance the effectiveness of other skincare ingredients.
In conclusion, the recent study on sweet cherry (Prunus avium L.) fruit extract provides valuable insights into the potential benefits of this natural ingredient for skincare. The results demonstrate that the extract has significant activity in epidermis function without posing risks for cytotoxicity or irritation. As the skincare industry continues to evolve and prioritize natural, eco-friendly alternatives, sweet cherry fruit extract may emerge as a key player in the development of innovative and effective skincare products.